Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(4-(1H-pyrrolo[2,3-b]pyridin-3-yl)piperidin-1-yl)-3-(5-(methylsulfonyl)-3-(4-(trifluoromethyl)phenyl)-4,5,6,7-tetrahydropyrazolo[4,3-c]pyridin-1-yl)propan-2-ol
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 PubChem ID
CID: 10210876
SID: 15208992
Canonical SMILES
CS(=O)(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCC(CC1)c1c[nH]c2ncccc12)-c1ccc(cc1)C(F)(F)F
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Compound Formula C29H33F3N6O3S
Compound Structure
Protein Name
 Protein Info 
Cathepsin S
Protein Classification
Enzyme
>
Protease
>
Cysteine protease
>
Cysteine protease CA clan
>
Cysteine protease C1A family
Uniprot ID
P25774
Gene Name
CTSS
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000147 JY
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 860 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 27 nM