Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-fluoro-3-(1-(3-(5-(methylsulfonyl)-3-(4-(trifluoromethyl)phenyl)-4,5,6,7-tetrahydropyrazolo[4,3-c]pyridin-1-yl)propyl)piperidin-4-yl)-N-(2-morpholinoethyl)benzo[b]thiophene-2-carboxamide
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 PubChem ID
CID: 10284032
SID: 15288961
Canonical SMILES
CS(=O)(=O)N1CCc2c(C1)c(nn2CCCN1CCC(CC1)c1c(sc2cc(F)ccc12)C(=O)NCCN1CCOCC1)-c1ccc(cc1)C(F)(F)F
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Compound Formula C37H44F4N6O4S2
Compound Structure
Protein Name
 Protein Info 
Cathepsin S
Protein Classification
Enzyme
>
Protease
>
Cysteine protease
>
Cysteine protease CA clan
>
Cysteine protease C1A family
Uniprot ID
P25774
Gene Name
CTSS
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000147 JY
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 340 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 39 nM