Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(1-(3-(3-(3,4-dichlorophenyl)-5-(methylsulfonyl)-4,5,6,7-tetrahydropyrazolo[4,3-c]pyridin-1-yl)propyl)piperidin-4-yl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one
    Show/Hide
 PubChem ID
CID: 22293729
Canonical SMILES
Cn1c2ccccc2n(C2CCN(CCCn3nc(c4CN(CCc34)S(C)(=O)=O)-c3ccc(Cl)c(Cl)c3)CC2)c1=O
    Show/Hide
Compound Formula C29H34Cl2N6O3S
Compound Structure
Protein Name
 Protein Info 
Cathepsin S
Protein Classification
Enzyme
>
Protease
>
Cysteine protease
>
Cysteine protease CA clan
>
Cysteine protease C1A family
Uniprot ID
P25774
Gene Name
CTSS
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000147 JY
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 800 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10 nM
2 IC50 = 50 nM