Brief Information of the Compound and Protein
Compound Name
2-(4-{3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenoxymethyl}phenyl)acetic acid
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PubChem ID
CID: 16090329
SID: 24736318
Canonical SMILES
OC(=O)Cc1ccc(COc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1
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Compound Formula C32H22F3NO4
Compound Structure
Protein Name
Oxysterols receptor LXR-beta
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group H
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Nuclear hormone receptor subfamily 1 group H member 3
Uniprot ID
P55055
Gene Name
NR1H2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 143 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5 nM