Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(3',4',-5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-yl)-N-(m-tolyl)acetamide
    Show/Hide
 PubChem ID
CID: 10425450
SID: 15444520
Canonical SMILES
Cc1cccc(NC(=O)CN2CCC(CC2)c2ccccn2)c1
    Show/Hide
Compound Formula C19H23N3O
Compound Structure
Protein Name
 Protein Info 
D(4) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P21917
Gene Name
DRD4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  4
1
EC50 = 2.7 nM
   TI
   LI
   LO
   TS
2
EC50 = 473 nM
   TI
   LI
   LO
   TS
3
IC50 = 68.4 nM
   TI
   LI
   LO
   TS
4
IC50 = 191 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  4
1
EC50 = 14 nM
   TI
   LI
   LO
   TS
2
Ki = 3.95 nM
   TI
   LI
   LO
   TS
3
Ki = 8 nM
   TI
   LI
   LO
   TS
4
Ki = 54.2 nM
   TI
   LI
   LO
   TS