Brief Information of the Compound and Protein
Compound Name
2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benzo[d]imidazole
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PubChem ID
CID: 5025739
SID: 14849264
Canonical SMILES
C(N1CCN(CC1)c1ccccn1)c1nc2ccccc2[nH]1
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Compound Formula C17H19N5
Compound Structure
Protein Name
D(4) dopamine receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P21917
Gene Name
DRD4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 12.4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 ~ 12.4 nM
2 Ki = 167 nM
3 Ki ~ 46.8 nM
4 Ki ~ 57.5 nM
5 Ki ~ 63.6 nM