Brief Information of the Compound and Protein
Compound Name
8-[(S)-1-(4-tert-Butyl-benzenesulfonyl)-pyrrolidin-3-yloxy]-quinolin-2-ylamine
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PubChem ID
CID: 44394807
Canonical SMILES
CC(C)(C)c1ccc(cc1)S(=O)(=O)N1CC[C@@H](C1)Oc1cccc2ccc(N)nc12
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Compound Formula C23H27N3O3S
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000863 I3.4.2 Homo sapiens (Human)  1
1
IC50 = 210 nM
   TI
   LI
   LO
   TS
CL000016 IMR-32 Homo sapiens (Human)  1
1
IC50 = 1140 nM
   TI
   LI
   LO
   TS