Brief Information of the Compound and Protein
Compound Name
N-(cyclopropylmethyl)-8-[1-[4-(2-methylpropyl)phenyl]pyrrolidin-3-yl]oxyquinolin-2-amine
    Show/Hide
PubChem ID
CID: 44394825
Canonical SMILES
CC(C)Cc1ccc(cc1)N1CCC(C1)Oc1cccc2ccc(NCC3CC3)nc12
    Show/Hide
Compound Formula C27H33N3O
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000863 I3.4.2 Homo sapiens (Human)  1
1
IC50 = 149 nM
   TI
   LI
   LO
   TS
CL000016 IMR-32 Homo sapiens (Human)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS