Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-Benzyl-4-(4-phenylpiperazin-1-yl)phthalazine
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 PubChem ID
CID: 6404568
SID: 85181646
Canonical SMILES
C(c1ccccc1)c1nnc(N2CCN(CC2)c2ccccc2)c2ccccc12
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Compound Formula C25H24N4
Compound Structure
Protein Name
 Protein Info 
Protein smoothened
Protein Classification
Membrane receptor
>
Frizzled family G protein-coupled receptor
>
Smoothened receptor (frizzled family GPCR)
Uniprot ID
P56726
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1095 nM
   TI
   LI
   LO
   TS
CL000633 TM3
 Cell Line Info 
Mus musculus (Mouse)  2
1
IC50 = 414 nM
   TI
   LI
   LO
   TS
2
IC50 = 2246 nM
   TI
   LI
   LO
   TS