Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-acetyl-4-[(4-but-2-ynoxyphenyl)sulfonylmethyl]-N-hydroxypiperidine-4-carboxamide
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 PubChem ID
CID: 9801569
SID: 14757531
Canonical SMILES
CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(C)=O)C(=O)NO
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Compound Formula C19H24N2O6S
Compound Structure
Protein Name
 Protein Info 
Disintegrin and metalloproteinase domain-containing protein 17
Protein Classification
Enzyme
>
Protease
>
Metallo protease
>
Metallo protease MAM clan
>
Metallo protease M12B subfamily
Uniprot ID
P78536
Gene Name
ADAM17
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.1 nM