Brief Information of the Compound and Protein
Compound Name
 Compound Info 
pyridin-3-ylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate
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 PubChem ID
CID: 4261
SID: 14804341
Canonical SMILES
Nc1ccccc1NC(=O)c1ccc(CNC(=O)OCc2cccnc2)cc1
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Compound Formula C21H20N4O3
Compound Structure
Protein Name
 Protein Info 
Histone deacetylase 2
Protein Classification
Epigenetic regulator
>
Eraser
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Histone deacetylase
>
HDAC class I
Uniprot ID
Q92769
Gene Name
HDAC2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 250 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 247 nM
   TI
   LI
   LO
   TS
2
IC50 = 505 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.2 nM
2 IC50 = 15 nM
3 IC50 = 250 nM
4 IC50 = 340 nM
5 IC50 = 396 nM
6 IC50 = 400 nM
7 IC50 = 410 nM
8 IC50 = 480 nM
9 IC50 = 500 nM
10 IC50 = 505 nM
11 IC50 = 613 nM
12 IC50 = 650 nM
13 IC50 = 720 nM
14 IC50 = 740 nM
15 IC50 = 1000 nM
16 IC50 = 1510 nM
17 IC50 < 300 nM
18 Ki = 6 nM
19 Ki = 65 nM
20 Ki = 73 nM
21 Ki = 590 nM