Brief Information of the Compound and Protein
Compound Name
2-(4-methylpiperazin-1-yl)-4-(naphthalen-1-ylsulfonyl)benzo[d]oxazole
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PubChem ID
CID: 24783809
SID: 49708173
Canonical SMILES
CN1CCN(CC1)c1nc2c(cccc2o1)S(=O)(=O)c1cccc2ccccc12
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Compound Formula C22H21N3O3S
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  2
1
IC50 = 105 nM
   TI
   LI
   LO
   TS
2
Ki = 9.7 nM
   TI
   LI
   LO
   TS