Brief Information of the Compound and Protein
Compound Name
 Compound Info 
8-[bis(2-chlorophenyl)methyl]-3-{2-[(cyclohexylmethyl)amino]ethyl}-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
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 PubChem ID
CID: 25190595
Canonical SMILES
Clc1ccccc1C(N1CCC2(CC1)N(CN(CCNCC1CCCCC1)C2=O)c1ccccc1)c1ccccc1Cl
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Compound Formula C35H42Cl2N4O
Compound Structure
Protein Name
 Protein Info 
Kappa-type opioid receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Opioid receptor
Uniprot ID
P41145
Gene Name
OPRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 271 nM
   TI
   LI
   LO
   TS