Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-Trifluoromethyl-N-(3-trifluoromethyl-benzyl)-benzamidine
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 PubChem ID
CID: 44374617
Canonical SMILES
NC(=NCc1cccc(c1)C(F)(F)F)c1ccc(cc1)C(F)(F)F
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Compound Formula C16H12F6N2
Compound Structure
Protein Name
 Protein Info 
Glutamate receptor ionotropic, NMDA 2B
Protein Classification
Ion channel
>
Ligand-gated ion channel
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Ionotropic glutamate receptor
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NMDA receptor
Uniprot ID
Q13224
Gene Name
GRIN2B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000309 NCTC clone 929
 Cell Line Info 
Mus musculus (Mouse)  1
1
Ki = 700 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 660 nM