Brief Information of the Compound and Protein
Compound Name
N'-[(3,5-dimethylphenyl)methyl]-4-(trifluoromethoxy)benzenecarboximidamide
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PubChem ID
CID: 9927159
SID: 14899380
Canonical SMILES
Cc1cc(C)cc(CN=C(N)c2ccc(OC(F)(F)F)cc2)c1
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Compound Formula C17H17F3N2O
Compound Structure
Protein Name
Glutamate receptor ionotropic, NMDA 2B
Protein Classification
Ion channel
>
Ligand-gated ion channel
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Ionotropic glutamate receptor
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NMDA receptor
Uniprot ID
Q13224
Gene Name
GRIN2B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000309 NCTC clone 929 Mus musculus (Mouse)  1
1
Ki = 1.2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.2 nM