Brief Information of the Compound and Protein
Compound Name
4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-carboxylic acid (4-nitro-phenyl)-amide
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PubChem ID
CID: 9911005
SID: 14881333
Canonical SMILES
COc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(cc3)[N+]([O-])=O)c2cc1OC
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Compound Formula C21H22N6O5
Compound Structure
Protein Name
Platelet-derived growth factor receptor beta
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P09619
Gene Name
PDGFRB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 700 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 240 nM
2 IC50 = 700 nM