Brief Information of the Compound and Protein
Compound Name
(E)-5-(butan-2-ylidene)-9-fluoro-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinoline
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PubChem ID
CID: 44305514
Canonical SMILES
CC\C(C)=C1\Oc2ccc(F)cc2-c2ccc3NC(C)(C)C=C(C)c3c12
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Compound Formula C23H24FNO
Compound Structure
Protein Name
Progesterone receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1 Chlorocebus aethiops (Green monkey)  2
1
EC50 = 27 nM
   TI
   LI
   LO
   TS
2
IC50 = 980 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 16.6 nM
2 Ki = 16.7 nM