Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[9-Fluoro-2,2,4-trimethyl-1,2-dihydro-6-oxa-1-aza-chrysen-(5Z)-ylidene]-propan-2-one
    Show/Hide
 PubChem ID
CID: 44305527
Canonical SMILES
CC(=O)/C=C1\Oc2ccc(F)cc2-c2ccc3c(c21)C(C)=CC(C)(C)N3
    Show/Hide
Compound Formula C22H20FNO2
Compound Structure
Protein Name
 Protein Info 
Progesterone receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
IC50 = 124 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki > 100 nM