Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S)-2-amino-3-(1H-imidazol-4-yl)-N-[(2R)-1-{1-methanesulfonyl-1,2-dihydrospiro[indole-3,4'-piperidine]-1'-yl}-3-(naphthalen-2-yl)-1-oxopropan-2-yl]propanamide
    Show/Hide
 PubChem ID
CID: 44361027
Canonical SMILES
CS(=O)(=O)N1CC2(CCN(CC2)C(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@@H](N)Cc2cnc[nH]2)c2ccccc12
    Show/Hide
Compound Formula C32H36N6O4S
Compound Structure
Protein Name
 Protein Info 
Melanocortin receptor 4
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Melanocortin receptor
Uniprot ID
P32245
Gene Name
MC4R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 108 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 108 nM
   TI
   LI
   LO
   TS