Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[2-[5-methoxy-2-[(3-methoxyphenyl)methyl]-1-benzofuran-3-yl]ethyl]acetamide
    Show/Hide
 PubChem ID
CID: 9998187
SID: 14977710
Canonical SMILES
COc1cccc(Cc2oc3ccc(OC)cc3c2CCNC(C)=O)c1
    Show/Hide
Compound Formula C21H23NO4
Compound Structure
Protein Name
 Protein Info 
Melatonin receptor type 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine-derivative receptor (family A GPCR)
>
Melatonin receptor
Uniprot ID
P48039
Gene Name
MTNR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 37 nM
   TI
   LI
   LO
   TS
2
Ki = 27 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 40.6 nM
   TI
   LI
   LO
   TS
CL000035 NIH 3T3
 Cell Line Info 
Mus musculus (Mouse)  1
1
Ki = 40.74 nM
   TI
   LI
   LO
   TS