Brief Information of the Compound and Protein
Compound Name
3-(Dimethylamino)propyl (2E)-4-{[4-(3-Bromoanilino)-6-quinazolinyl]amino}-4-oxo-2-butenoate
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PubChem ID
CID: 5329085
SID: 15605398
Canonical SMILES
CN(C)CCCOC(=O)\C=C\C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1
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Compound Formula C23H24BrN5O3
Compound Structure
Protein Name
Receptor tyrosine-protein kinase erbB-2
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase EGFR family
Uniprot ID
P04626
Gene Name
ERBB2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000284 MDA-MB-453 Homo sapiens (Human)  1
1
IC50 = 110 nM
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