Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-{5-[(R)-2-(1-{4-[2-(N',N'-Dimethyl-guanidino)-4-oxo-4H-thiazol-5-ylidenemethyl]-phenyl}-piperidin-4-ylamino)-1-hydroxy-ethyl]-2-hydroxy-phenyl}-methanesulfonamide
    Show/Hide
 PubChem ID
CID: 44386631
Canonical SMILES
CN(C)C(=N)NC1=NC(=O)/C(=C/c2ccc(N3CCC(NC[C@H](O)c4ccc(O)c(NS(C)(=O)=O)c4)CC3)cc2)S1
    Show/Hide
Compound Formula C27H35N7O5S2
Compound Structure
Protein Name
 Protein Info 
Beta-3 adrenergic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Adrenergic receptor
Uniprot ID
P13945
Gene Name
ADRB3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 3 nM
   TI
   LI
   LO
   TS