Brief Information of the Compound and Protein
Compound Name
N-methyl-N-[(E,2R)-1-naphthalen-2-yl-5-oxo-5-[[(3R)-2-oxoazepan-3-yl]amino]pent-3-en-2-yl]-3,5-bis(trifluoromethyl)benzamide
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PubChem ID
CID: 44335372
Canonical SMILES
CN([C@H](Cc1ccc2ccccc2c1)\C=C\C(=O)N[C@@H]1CCCCNC1=O)C(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F
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Compound Formula C31H29F6N3O3
Compound Structure
Protein Name
Substance-K receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P21452
Gene Name
TACR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 60 nM
   TI
   LI
   LO
   TS