Brief Information of the Compound and Protein
Compound Name
2-ethyl-5-methoxy-N,N-dimethyltryptamine
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PubChem ID
CID: 6918513
SID: 15196611
Canonical SMILES
CCc1[nH]c2ccc(OC)cc2c1CCN(C)C
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Compound Formula C15H22N2O
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  3
1
IC50 = 85 nM
   TI
   LI
   LO
   TS
2
Ki = 16 nM
   TI
   LI
   LO
   TS
3
Ki = 52 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 85 nM
2 Ki = 16 nM
3 Ki < 50 nM