Brief Information of the Compound and Protein
Compound Name
8,9-Dichloro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,2-a]quinoxalin-5-one
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PubChem ID
CID: 3906894
SID: 14750576
Canonical SMILES
Clc1cc2NC(=O)C3CNCCN3c2cc1Cl
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Compound Formula C11H11Cl2N3O
Compound Structure
Protein Name
5-hydroxytryptamine receptor 2C
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P28335
Gene Name
HTR2C
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 12 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
Ki = 4 nM
   TI
   LI
   LO
   TS
2
Ki = 58 nM
   TI
   LI
   LO
   TS