Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-tert-Butyl-N-(5-methyl-4-methylsulfanyl-isoxazol-3-yl)-benzenesulfonamide
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 PubChem ID
CID: 44298394
Canonical SMILES
CSc1c(C)onc1NS(=O)(=O)c1ccc(cc1)C(C)(C)C
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Compound Formula C15H20N2O3S2
Compound Structure
Protein Name
 Protein Info 
Endothelin receptor type B
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P35463
Gene Name
EDNRB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
IC50 = 35000 nM
   TI
   LI
   LO
   TS