Brief Information of the Compound and Protein
Compound Name
4-tert-Butyl-N-[5-(3-hydroxy-propyl)-4-(3-methoxy-phenylsulfanyl)-isoxazol-3-yl]-benzenesulfonamide
    Show/Hide
PubChem ID
CID: 44298381
Canonical SMILES
COc1cccc(Sc2c(NS(=O)(=O)c3ccc(cc3)C(C)(C)C)noc2CCCO)c1
    Show/Hide
Compound Formula C23H28N2O5S2
Compound Structure
Protein Name
Endothelin-1 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Endothelin receptor
Uniprot ID
P26684
Gene Name
EDNRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000238 A7r5 Rattus norvegicus (Rat)  1
1
IC50 = 320 nM
   TI
   LI
   LO
   TS