Brief Information of the Compound and Protein
Compound Name
(2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid
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PubChem ID
CID: 10255
SID: 15220270
Canonical SMILES
CC(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O
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Compound Formula C10H15NO4
Compound Structure
Protein Name
Glutamate receptor ionotropic, kainate 2
Protein Classification
Ion channel
>
Ligand-gated ion channel
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Ionotropic glutamate receptor
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Kainate receptor
Uniprot ID
Q13002
Gene Name
GRIK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  3
1
EC50 = 700 nM
   TI
   LI
   LO
   TS
2
Ki = 32 nM
   TI
   LI
   LO
   TS
3
Ki = 32.4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 53 nM