Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-enyl)benzoic acid
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 PubChem ID
CID: 5289501
SID: 14778420
Canonical SMILES
C\C(=C/c1ccc(cc1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C
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Compound Formula C24H28O2
Compound Structure
Protein Name
 Protein Info 
Retinoic acid receptor alpha
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group B
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Nuclear hormone receptor subfamily 1 group B member 1
Uniprot ID
P10276
Gene Name
RARA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  2
1
AC50 = 200 nM
   TI
   LI
   LO
   TS
2
EC50 = 30 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 0.18 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 21 nM
2 EC50 = 30 nM
3 EC50 = 85 nM
4 IC50 = 36 nM
5 Kd = 36 nM
6 Ki = 21 nM