Brief Information of the Compound and Protein
Compound Name
1-Phenyl-8-(1,2,3,4-tetrahydro-naphthalen-1-yl)-1,3,8-triaza-spiro[4.5]decan-4-one
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PubChem ID
CID: 9947044
SID: 14921543
Canonical SMILES
O=C1NCN(c2ccccc2)C11CCN(CC1)C1CCCc2ccccc12
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Compound Formula C23H27N3O
Compound Structure
Protein Name
Kappa-type opioid receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Opioid receptor
Uniprot ID
P41145
Gene Name
OPRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 65 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 10.7 nM
   TI
   LI
   LO
   TS