Brief Information of the Compound and Protein
Compound Name
2-benzyl-3-[2-(3,4-dihydro-1H-[1]benzofuro[3,2-c]pyridin-2-yl)ethyl]pyrido[1,2-a]pyrimidin-4-one
    Show/Hide
PubChem ID
CID: 44376975
Canonical SMILES
O=c1c(CCN2CCc3oc4ccccc4c3C2)c(Cc2ccccc2)nc2ccccn12
    Show/Hide
Compound Formula C28H25N3O2
Compound Structure
Protein Name
Alpha-2B adrenergic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Adrenergic receptor
Uniprot ID
P18089
Gene Name
ADRA2B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 4.169 nM
   TI
   LI
   LO
   TS