Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(4R,5S)-5-(4-Chloro-phenyl)-2,2,4-trimethyl-2,3,4,5-tetrahydro-1H-6-oxa-1-aza-chrysene
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 PubChem ID
CID: 10548404
SID: 15575427
Canonical SMILES
C[C@@H]1CC(C)(C)Nc2ccc3-c4ccccc4O[C@@H](c4ccc(Cl)cc4)c3c12
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Compound Formula C25H24ClNO
Compound Structure
Protein Name
 Protein Info 
Progesterone receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  2
1
EC50 = 48 nM
   TI
   LI
   LO
   TS
2
IC50 = 3100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 91 nM