Brief Information of the Compound and Protein
Compound Name
5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2-(3-hydroxy-phenyl)-pentanenitrile
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PubChem ID
CID: 10833944
SID: 15875312
Canonical SMILES
Oc1cccc(c1)C(CCCN1CCC(O)(CC1)c1ccc(Cl)cc1)C#N
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Compound Formula C22H25ClN2O2
Compound Structure
Protein Name
C-C chemokine receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P32246
Gene Name
CCR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 9000 nM
   TI
   LI
   LO
   TS
2
Ki = 156 nM
   TI
   LI
   LO
   TS