Brief Information of the Compound and Protein
Compound Name
2-{4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-cyano-butyl}-benzonitrile
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PubChem ID
CID: 10572669
SID: 15600759
Canonical SMILES
OC1(CCN(CCCC(C#N)c2ccccc2C#N)CC1)c1ccc(Cl)cc1
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Compound Formula C23H24ClN3O
Compound Structure
Protein Name
C-C chemokine receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P32246
Gene Name
CCR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 5800 nM
   TI
   LI
   LO
   TS
2
Ki = 98 nM
   TI
   LI
   LO
   TS