Brief Information of the Compound and Protein
Compound Name
11-{3-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-propyl}-6,11-dihydro-dibenzo[b,e]oxepine-11-carbonitrile
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PubChem ID
CID: 9956488
SID: 14932145
Canonical SMILES
OC1(CCN(CCCC2(C#N)c3ccccc3COc3ccccc23)CC1)c1ccc(Cl)cc1
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Compound Formula C29H29ClN2O2
Compound Structure
Protein Name
C-C chemokine receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P32246
Gene Name
CCR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 7700 nM
   TI
   LI
   LO
   TS
2
Ki = 34 nM
   TI
   LI
   LO
   TS