Brief Information of the Compound and Protein
Compound Name
2-(3-Bromo-4-methoxy-phenyl)-5-[4-(4-chloro-phenyl)-4-hydroxy-piperidin-1-yl]-pentanenitrile
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PubChem ID
CID: 10766998
SID: 15804581
Canonical SMILES
COc1ccc(cc1Br)C(CCCN1CCC(O)(CC1)c1ccc(Cl)cc1)C#N
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Compound Formula C23H26BrClN2O2
Compound Structure
Protein Name
C-C chemokine receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P32246
Gene Name
CCR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 1900 nM
   TI
   LI
   LO
   TS
2
Ki = 74 nM
   TI
   LI
   LO
   TS