Brief Information of the Compound and Protein
Compound Name
N-[4-(4-phenoxyanilino)quinazolin-6-yl]prop-2-enamide
    Show/Hide
PubChem ID
CID: 10547930
SID: 15574931
Canonical SMILES
C=CC(=O)Nc1ccc2ncnc(Nc3ccc(Oc4ccccc4)cc3)c2c1
    Show/Hide
Compound Formula C23H18N4O2
Compound Structure
Protein Name
Receptor tyrosine-protein kinase erbB-2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P04626
Gene Name
ERBB2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000284 MDA-MB-453 Homo sapiens (Human)  1
1
IC50 = 8.6 nM
   TI
   LI
   LO
   TS