Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-anilinoquinazoline deriv. 2
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 PubChem ID
CID: 4708
SID: 14877295
Canonical SMILES
Brc1cccc(Nc2ncnc3ccc(NC(=O)C=C)cc23)c1
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Compound Formula C17H13BrN4O
Compound Structure
Protein Name
 Protein Info 
Receptor tyrosine-protein kinase erbB-2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P04626
Gene Name
ERBB2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000284 MDA-MB-453
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 5.7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 24 nM
2 IC50 = 114 nM