Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-((3R,4R)-1-Cyclooctylmethyl-3-hydroxymethyl-piperidin-4-yl)-3-ethyl-1,3-dihydro-benzoimidazol-2-one
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 PubChem ID
CID: 5311194
SID: 49684203
Canonical SMILES
CCn1c2ccccc2n([C@@H]2CCN(CC3CCCCCCC3)C[C@H]2CO)c1=O
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Compound Formula C24H37N3O2
Compound Structure
Protein Name
 Protein Info 
Nociceptin receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Opioid receptor
Uniprot ID
P41146
Gene Name
OPRL1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  6
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
2
IC50 = 1.5 nM
   TI
   LI
   LO
   TS
3
IC50 = 2.3 nM
   TI
   LI
   LO
   TS
4
IC50 = 2.4 nM
   TI
   LI
   LO
   TS
5
IC50 = 5.6 nM
   TI
   LI
   LO
   TS
6
Ki = 0.403 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 2.3 nM
   TI
   LI
   LO
   TS