Brief Information of the Compound and Protein
Compound Name
 Compound Info 
8-ethyl-4-(trifluoromethyl)-6,7,8,9-tetrahydropyrano[3,2-g]quinolin-2-one
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 PubChem ID
CID: 44264273
Canonical SMILES
CCC1CCc2cc3c(cc(=O)oc3cc2N1)C(F)(F)F
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Compound Formula C15H14F3NO2
Compound Structure
Protein Name
 Protein Info 
Androgen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 4
Uniprot ID
P10275
Gene Name
AR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000880 COS
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
CL000044 CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  2
1
EC50 = 7 nM
   TI
   LI
   LO
   TS
2
IC50 > 10 nM
   TI
   LI
   LO
   TS