Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[(E)-(3-Phenyl-acryloyl)amino]-1H-[1,2,4]triazole-3-carboxylic acid {(S)-1-[(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-4-guanidino-butylcarbamoyl]-2-cyclohexyl-ethyl}-amide
    Show/Hide
 PubChem ID
CID: 9875040
SID: 14839987
Canonical SMILES
N=C(N)NCCC[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)c1n[nH]c(NC(=O)/C=C/c2ccccc2)n1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
    Show/Hide
Compound Formula C36H47N11O5
Compound Structure
Protein Name
 Protein Info 
Proteinase-activated receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Protease-activated receptor
>
Protease-activated receptor
Uniprot ID
P25116
Gene Name
F2R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000812 CHRF
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 6400 nM
   TI
   LI
   LO
   TS