Brief Information of the Compound and Protein
Compound Name
1-Methyl-5-[4-(3-phenyl-prop-2-ynyloxy)-[1,2,5]thiadiazol-3-yl]-1,2,3,6-tetrahydro-pyridine
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PubChem ID
CID: 10686494
SID: 15720128
Canonical SMILES
CN1CCC=C(C1)c1nsnc1OCC#Cc1ccccc1
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Compound Formula C17H17N3OS
Compound Structure
Protein Name
Muscarinic acetylcholine receptor M1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Acetylcholine receptor
Uniprot ID
P11229
Gene Name
CHRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000398 A-9 Mus musculus (Mouse)  1
1
EC50 = 110 nM
   TI
   LI
   LO
   TS
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 37.15 nM
   TI
   LI
   LO
   TS
2
IC50 = 2137.96 nM
   TI
   LI
   LO
   TS