Brief Information of the Compound and Protein
Compound Name
 Compound Info 
CAS_3853
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 PubChem ID
CID: 5311200
SID: 57304374
Canonical SMILES
Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1
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Compound Formula C18H19ClN4
Compound Structure
Protein Name
 Protein Info 
D(2) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  6
1
Ki = 908 nM
   TI
   LI
   LO
   TS
2
Ki = 960 nM
   TI
   LI
   LO
   TS
3
Ki = 33000 nM
   TI
   LI
   LO
   TS
4
Ki = 38000 nM
   TI
   LI
   LO
   TS
5
Ki = 47000 nM
   TI
   LI
   LO
   TS
6
Ki = 54000 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 1621.81 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 448 nM
2 Ki = 920 nM
3 Ki = 960 nM
4 Ki = 53703.18 nM