Brief Information of the Compound and Protein
Compound Name
(5,8-difluoro-2,2,4-trimethyl-1,10-dihydroindeno[1,2-g]quinolin-10-yl) 2,2,2-trifluoroacetate
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PubChem ID
CID: 44325290
Canonical SMILES
CC1=CC(C)(C)Nc2cc3C(OC(=O)C(F)(F)F)c4cc(F)ccc4-c3c(F)c12
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Compound Formula C21H16F5NO2
Compound Structure
Protein Name
Progesterone receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1 Chlorocebus aethiops (Green monkey)  1
1
IC50 = 46 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 62.5 nM