Brief Information of the Compound and Protein
Compound Name
1-(2,2,4-Trimethyl-2,10-dihydro-1H-indeno[1,2-g]quinolin-8-yl)-ethanone
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PubChem ID
CID: 15458741
Canonical SMILES
CC(=O)c1ccc-2c(Cc3cc4NC(C)(C)C=C(C)c4cc-23)c1
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Compound Formula C21H21NO
Compound Structure
Protein Name
Progesterone receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1 Chlorocebus aethiops (Green monkey)  1
1
IC50 = 164 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 176 nM
2 Ki = 177.83 nM