Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one; hydrochloride
    Show/Hide
 PubChem ID
CID: 10091417
SID: 15078607
Canonical SMILES
Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1cccc2OCCOc12
    Show/Hide
Compound Formula C22H25FN2O3
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 5.248 nM
   TI
   LI
   LO
   TS
2
EC50 = 7.413 nM
   TI
   LI
   LO
   TS