Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-Chloro-3-(4-methanesulfonyl-phenyl)-6''-methyl-[2,3'']bipyridinyl
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 PubChem ID
CID: 123619
SID: 14828179
Canonical SMILES
Cc1ccc(cn1)-c1ncc(Cl)cc1-c1ccc(cc1)S(C)(=O)=O
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Compound Formula C18H15ClN2O2S
Compound Structure
Protein Name
 Protein Info 
Prostaglandin G/H synthase 2
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
P35354
Gene Name
PTGS2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 81 nM
   TI
   LI
   LO
   TS
CL000880 COS
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
IC50 = 347 nM
   TI
   LI
   LO
   TS
CL000058 T-REx-293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 560 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 430 nM
2 IC50 = 1100 nM
3 Ki = 69 nM