Brief Information of the Compound and Protein
Compound Name
5-(3-Methyl-[1,2,4]oxadiazol-5-yl)-1,4,5,6-tetrahydro-pyrimidine TFA
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PubChem ID
CID: 9838580
SID: 14799613
Canonical SMILES
Cc1noc(C2CN=CNC2)n1.O=C(O)C(F)(F)F
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Compound Formula C9H11F3N4O3
Compound Structure
Protein Name
Muscarinic acetylcholine receptor M1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Acetylcholine receptor
Uniprot ID
P12657
Gene Name
CHRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000398 A-9 Mus musculus (Mouse)  4
1
EC50 = 5400 nM
   TI
   LI
   LO
   TS
2
Ki = 2.31 nM
   TI
   LI
   LO
   TS
3
Ki = 2.5 nM
   TI
   LI
   LO
   TS
4
Ki = 21.1 nM
   TI
   LI
   LO
   TS