Brief Information of the Compound and Protein
Compound Name
5-Benzo[1,3]dioxol-5-ylmethyl-7-(3,4-dimethoxy-phenylsulfanyl)-5H-[1,3]dioxolo[4,5-f]indole-6-carboxylic acid
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PubChem ID
CID: 18995992
Canonical SMILES
COc1ccc(Sc2c(C(O)=O)n(Cc3ccc4OCOc4c3)c3cc4OCOc4cc23)cc1OC
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Compound Formula C26H21NO8S
Compound Structure
Protein Name
Endothelin-1 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P25101
Gene Name
EDNRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000041 LTK- Mus musculus (Mouse)  1
1
IC50 = 41 nM
   TI
   LI
   LO
   TS