Brief Information of the Compound and Protein
Compound Name
2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-tolyl-piperazin-1-yl)-ethanone
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PubChem ID
CID: 10385855
SID: 15401310
Canonical SMILES
Cc1ccccc1N1CCN(CC1)C(=O)COc1ccc2[nH]cc(CCN)c2c1
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Compound Formula C23H28N4O2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 1D
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P28221
Gene Name
HTR1D
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 0.6 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.8 nM
2 Ki = 0.87 nM
3 Ki = 2.08 nM
4 Ki = 2.1 nM